由甲醇/二甲醚通过催化氧化合成高附加值含氧化学品（如甲醛、甲酸甲酯、甲缩醛、聚甲氧基二甲醚等），具有原子经济性好、产品有特色、碳排放低的优势，作为高值利用途径得到了广泛关注。在甲醇/二甲醚氧化转化的过程中也面临着一系列挑战，包括低温下C−H键活化困难、高温时易发生深度氧化，以及更大分子产物中C−O键的可控链增长难度大等问题。本综述将重点介绍相关研究团队在低温下甲醇/二甲醚分子中C−H键的活化断键规律以及在更长C−O键可控链增长方面的最新研究进展，勾勒出几个代表性催化反应机制的概貌，以期为这一领域及相关研究提供有价值的参考。

The synthesis of high-value-added oxygenated chemicals (such as formaldehyde, methyl formate, dimethoxymethane, polymethoxy dimethyl ether, etc.) from methanol/dimethyl ether through an oxidative route boasts advantages of high atom utilization efficiency, distinctive product characteristics, and low carbon emissions, attracting significant attention as a pathway for high-value utilization. However, the oxidation conversion of methanol/dimethyl ether also confronts several challenges, including difficulty in activating C−H bonds at low temperatures, susceptibility to deep oxidation at high temperatures, and difficulty in controlling the chain growth of C−O bonds in larger molecular products. This review will focus on the latest progress in elucidating the mechanisms of the activation and cleavage of C−H bonds in methanol/dimethyl ether molecules at low temperatures and the controllable chain growth of longer C−O bonds by relevant research teams. It aims to outline several representative catalytic reaction mechanisms, thereby providing valuable insights for this field and related research endeavors.