Harbin Medical University University School of Chemical Engineering

金鸡纳碱（Quinine，又名奎宁），是一种用于治疗与预防疟疾的药物。研究金鸡纳碱分子结构。开展了金鸡纳碱分子结构的中红外（MIR）光谱研究。实验发现，金鸡纳碱分子结构的红外吸收模式主要包括：ν■、ν■、ν■、ν■、ν■、ν■、δ■、δ■、δ■、ν■和ρ■。研究发现，金鸡纳碱分子结构的去卷积MIR光谱的谱图分辨能力优于一维MIR光谱、二阶导数MIR光谱及四阶导数MIR光谱，并能提供更加丰富的光谱信息。MIR光谱开展了医药（金鸡纳碱）分子结构研究，具有重要的应用研究价值。

Cinchona alkaloid also known as quinine, is a drug used for the treatment and prevention of malaria. The molecular structure of quinine was studied. The molecular structure of quinine was researched by mid infrared (MIR) spectroscopy. The experiment found that the infrared absorption modes of quinine molecular structure mainly include: ν■, ν■, ν■, ν■, ν■, ν■, δ■, δ■, δ■, ν■and ρ■. Research has found that the deconvolution MIR spectroscopy of quinine molecular structure has better spectral resolution than one-dimensional MIR spectroscopy, second derivative MIR spectroscopy and fourth derivative MIR spectroscopy, and can provide richer spectral information. MIR spectroscopy has conducted research on the molecular structure of quinine in medicine, which has important application research value.

李明航1，柴嘉欣2，吉一帆2，常利双2，宗雪晴2，张泽旺2，王静伟2，徐元媛2. 金鸡纳碱分子结构研究[J]. 煤炭与化工, 2023, 46(12): 137-144.

Li Minghang1, Chai Jiaxin2, JI Yifan2, Chang Lishuang2, Zong Xueqing2, Zhang Zewang2, Wang Jingwei2, Xu Yuanyuan2*. Study on the molecular structure of quinine. CCI, 2023, 46(12): 137-144.